The Stone-von Neumann Theorem states that a Hilbert space on which is defined an irreducible set of operators which satisfy the exponentiated canonical commutation relations is unitarily equivalent to $L^2(R^n)$.
One such space is the Segal-Bargmann Space, which is the space of holomorphic functions that have finite norm under the inner product given by:
$$ (F,G) = \int_{C^n} \overline{F}(z) G(z) e^{-|z|^2} \mathrm{d}z $$
As explained in the Wikipedia article elements of this space can be thought of as functions on phase space (since $C^n$ is $2n$-dimensional) which seems like a more (or at least as useful) description of wave functions as in $L^2(R^n)$, given that Quantum Mechanics is based on Hamiltonian formalism.
Also the fact that functions are holomorphic seems like it's easier to define differential operators (rather than using a dense subspace). I've just finished taking an undergraduate course in Quantum Mechanics but it seems to me like this space a lot of advantages but I've never heard it mentioned in a lecture or in any common QM book. Why is this so? Is there something I'm missing which actually makes this space more complicated to use?