Applebee is a surname. Notable people with the surname include:
- Caroline Maria Applebee (c. 1785–1854), British artist
- Constance Applebee (1873–1981), US-based British academic athletic director
- Frank W. Applebee (1902–1988), American painter
- Kelly Applebee (born 1982), Australian cricketer
See also
- Applebee's, American restaurant company
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