It is well known that for if any two linear maps $V_1,V_2:\mathbb C^n\to\mathbb C^k\otimes\mathbb C^m$ (isometry or not) satisfy $$ {\rm tr}_{\mathbb C^m}(V_1(\cdot)V_1^\dagger)={\rm tr}_{\mathbb C^m}(V_2(\cdot)V_2^\dagger) \tag1 $$ then there exists $U\in\mathbb C^{m\times m}$ unitary such that $V_1=({\bf1}\otimes U)V_2$; cf. Corollary 2.24 in the book "The Theory of Quantum Information" by Watrous (alt link). In particular this shows that any two Stinespring isometries (cf. also here) which give rise to the same channel are locally unitarily equivalent in the above sense. Equivalently, any two sets of Kraus operators to the same channel can be transformed into each other using said unitary $U$, cf. here and here.
Equally as common as defining channels via Kraus operators is to use the environmental form (cf. also here and here), that is, to express $\Phi={\rm tr}_E(U((\cdot)\otimes\omega)U^\dagger)$ for some environment state $\omega$ and some system-environment unitary $U$. Here one can ask a similar
Question. Given two unitaries $U_1,U_2$ such that $$ {\rm tr}_E(U_1((\cdot)\otimes\omega)U_1^\dagger)={\rm tr}_E(U_2((\cdot)\otimes\omega)U_2^\dagger) \tag2 $$ in what sense are $U_1,U_2$ equivalent? (Actually, one can make things even more general by allowing for different environment states $\omega_1,\omega_2$ but let us keep things as are for now.)
A simple partial answer is the following: In the special case of a pure state $\omega=|\psi\rangle\langle\psi|$ the environmental form from (2) boils down to the isometry form from (1) because $\rho\otimes|\psi\rangle\langle\psi|=\iota_\psi\rho\iota_\psi^\dagger$ with $\iota_\psi|x\rangle:=|x\rangle\otimes|\psi\rangle$ meaning (1) holds with $V_j=U_j\iota_\psi$. Thus (2) implies that there exists a unitary $U$ on the environment such that $$ U_1({\bf1}\otimes|\psi\rangle)=U_1\iota_\psi=({\bf1}\otimes U)U_2\iota_\psi=({\bf1}\otimes U)U_2({\bf1}\otimes|\psi\rangle)\,.\tag3 $$ This is the best one can hope for because the other "columns" of $U_1,U_2$ do not contribute to (2) meaning they can be chosen arbitrarily, i.e. in general there exists no environment $U$ such that $U_1=({\bf1}\otimes U)U_2$.
There is, however, a special case where one may be able to say more: when $\omega$ is a full-rank state. Intuitively, in this case "all information from $U$ is used" to define the channel which is undermined by the fact that in the full-rank case the environmental form defines a unitary channel if and only if the system-environment unitary is of product form. Thus if the original channel is unitary and $\omega$ is full rank, then $U_1=({\bf1}\otimes U)U_2$ does in fact hold.
In general, however, it may happen that there is an additional local unitary "on the other side": trivially, if $[W,\omega]=0$, then $U_1$ and $U_1({\bf1}\otimes W)$ induce the same channel through different unitaries where $U_1({\bf1}\otimes W)\neq({\bf1}\otimes U)U_1$ for any $U$. This leads to the following
Question (refined). Given a full-rank state $\omega\in\mathbb C^{m\times m}$ as well as unitaries $U_1,U_2\in\mathbb C^{n\times n}\otimes\mathbb C^{m\times m}$ such that $$ {\rm tr}_E(U_1((\cdot)\otimes\omega)U_1^\dagger)={\rm tr}_E(U_2((\cdot)\otimes\omega)U_2^\dagger) $$ do there exist environment unitaries $U,W\in\mathbb C^{m\times m}$ with $[W,\omega]=0$ such that $U_1=({\bf1}\otimes U)U_2({\bf1}\otimes W)$?
(This is a Q&A style question meant as a contribution to the list of counterexamples in quantum information)