To construct a controlled gate with qubits in-between, you can use the following general form for a controlled gate:
$$U = |0\rangle\langle0| \otimes I + |1\rangle\langle1| \otimes G$$
Here, $|0\rangle\langle0|$ and $|1\rangle\langle1|$ are the projectors onto the states $|0\rangle$ and $|1\rangle$, respectively, and $I$ is the identity matrix.
$G$ is the gate you want to apply when the control qubit is in state $|1\rangle$.
Let's say you want to apply a controlled-NOT (CNOT) gate between qubits $q_1$ and $q_3$ with $q_2$ in-between.
The controlled-NOT gate $G$ is represented as:
$$\text{CNOT} = \begin{pmatrix} 1 & 0 & 0 & 0 \\ 0 & 1 & 0 & 0 \\ 0 & 0 & 0 & 1 \\ 0 & 0 & 1 & 0 \end{pmatrix}$$
The operator $U$ for this arrangement would be:
$$U = |0\rangle\langle0| \otimes I_2 + |1\rangle\langle1| \otimes \text{CNOT}$$
Here, $I_2$ is the 2x2 identity matrix. I hope this helps! Let me know if you need further clarification.