For a two-qubit state, there's a very straightforward method. If the state is separable, that means you can write it as
$$
|\psi\rangle\otimes|\phi\rangle=\alpha|0\rangle\otimes|\phi\rangle+\beta|1\rangle\otimes|\phi\rangle.
$$
So, if you look at your state, you look at the $|0\rangle\otimes |0\rangle$ term and say "$|\phi\rangle$ must be $|0\rangle$". But that is inconsistent with the $|1\rangle\otimes |+\rangle$ term. So, the state is not separable, so it is entangled.
If you have a more complex state, I suggest another method. Write out the coefficients of the state in a matrix. In this case,
$$
C=\begin{bmatrix} \frac{1}{\sqrt{2}} & 0 \\ \frac12 & \frac12 \end{bmatrix}
$$
Now if you calculate $\text{Tr}(CC^\dagger CC^\dagger)$ and you get the answer 1, the state is separable. Otherwise, it's entangled. (Why? $CC^\dagger$ is the same as the reduced density matrix on the first qubit, so you're measuring the purity of the first qubit. If it's pure, the state is separable. If it's mixed, the overall state is entangled.)