To answer A, lets start from basic ideal gas law equation,
$$ \tag 1 p = m\frac {RT}{VM} ,$$
Now differentiate with respect to time both sides (assuming $T=\text{const}$),
$$ \tag 2 \frac{dp}{dt} = \frac {RT}{VM}\cdot \frac{dm}{dt},$$
$\dot m$ is gas mass flow rate (negative in this case) through the hole, so lets sub it into (2),
$$ \tag 3 \frac{dp}{dt} = -\frac {RT}{VM}\cdot \rho v A,$$
As per same ideal gas law,- density of gas is simply $\rho=pM/RT$, using it in (3) and canceling terms we get,
$$ \tag 4 \frac {dp}{dt} = -\frac {pvA}{V} ,$$
Re-arranging (4) and then integrating both sides, while resolving integration constant in LHS
$$ \tag 5 \int \frac {dp}{p} = - \int_0^t \frac {vA}{V} dt,$$
gives (assuming constant gas flow speed $v$, which not necessarily true, but as a first approximation),
$$ \tag 6 \ln\left(\frac{p}{p_0}\right) = - \frac {vA}{V} t,$$
This gets us to the final equation of pressure in the room with hole vs time :
$$ \tag 7 p = p_0 \exp\left(- \frac {vA}{V} t\right) ,$$
where $A$ is hole area, and $V$ is room volume.
Exercises for the post author:
Do not assume temperature a constant, since when room will be open to the vacuum, room temperature should equalize to the vacuum temperature, which is $2.7K$,- if we take as a reference CMB. In this case one needs to use product rule of differentials in (2) and then somehow to resolve $dT/dt$, i.e. finding function of $T(t)$.
In integration (5),- do not assume that gas flow speed from the room hole into vacuum is constant, since when pressure will decrease, gas outflow speed $v(t)$ should also decrease too and so after finding flow speed profile vs time we need to use that expression in (5) integration, instead of just assuming it constant and moving it out of integral.
Discard ideal gas law and use real gas equation, like Van der Waals equation to see what happens when gas molecules are considered not a point particles.
In the end,- real $p(t)$ dependence can be a way more complex and probably follows exponential law only for the first moments of flow, then it should fallback to other mechanisms.