Of course there are differences.
Experiencing g on an upwards moving disk and experiencing g because moving upwards(=outwards) on a rotating, spherical surface, a globe, you are standing on and on which the gravitational pull of that mass counteracts that outward motion, is not logically equivalent.
The sensations are the same (and it is mathematically equivalent), but only as long as you are on the surface of either the disk or the globe. And you are not accelerating otherwise. Only free falling towards the surface of the disk feels the same as on the globe.
Also, it makes no sense that the disk should be moving upwards, if the disk is intended to have the same mass as the globe has. By moving upwards, the resulting gravity has the same direction (downward) as the gravitational force because of the mass has. Thus it would double the g force downwards. To make any sense, and assuming the disk has mass, this one has to fall/move downwards. This downward speed and the resulting accelerating force acting upwards together with the gravitational pull have to cancel each other out at 1g on the surface.
However, the following assumes the OP's stated scenario of a massless disk moving upwards in space and generating 1g at the surface.
The primary difference between both cases (disk vs. globe) is, that the disk only has one force to "simulate" gravity (moving upwards), while the globe has two (gravity and rotation/centrifugal acceleration).
Digging Holes
Imagine the disk being truly flat, of finite thickness and homogeneous mass distribution (but without weight). Now dig an imaginary hole downwards. Keep digging until you reach the other end. Because the disk is moving upwards you will experience the same 1g all the way down. Eventually you fall through the disk and end up being in weightlessness of space. The disk will continue its way without you.
Imagine the globe and dig a hole there. If you dig deeper you will experience a different g at increasing depths. You will feel lighter. At the center you experience total weightlessness and if you keep "digging down" you will experience increasing g again until it normalizes at the other side of the globe. You will continue staying on the globe.
You experience exactly one g only at the surface of the globe, because gravity from the mass of the planet and the rotational speed of the planet lift each other in a way that the gravitation towards the planet ends up 9.81 times higher than the centrifugal acceleration of the rotating planet also acting upon you.
Shooting Rockets into Orbit
If you imagine a rocket shot to orbit in a straight line upwards from the surface, this will also be different.
In the case of an upwards moving disk, there is no secondary force acting upon the rocket. As soon as you stop your thrusters, you will start "falling down" again (actually the disk is coming towards you), no matter on what orbit height you are.
In the case of the globe, this is different. At a certain orbit height you can deactivate your thrusters, because your centrifugal force (=velocity on that orbit) and the gravitation towards the planet have found another equilibrium to lift each other to almost 0. In this case, you are "free falling" around the globe all the time, without the need of external accelerations (=thrust).
Atmosphere
Atmosphere on a disk moving upwards in space will just be "compressed" and flow down at all sides. If the disk would be rotating, the atmosphere will be "spun off" to all sides as well.
On a globe this is different. The atmosphere is kept at the globe because every atom of it is subjected to the gravitational force towards the globe and its rotational force (centrifugal force) around its axis.
Acceleration
Imagine a Ferris wheel standing vertically, the seats are hanging free, always pointed down towards the ground. The wheel is spinning reasonable fast to let you feel force pushing you into the seat while spinning upwards. There is only one person (or a large mass) sitting in it which we focus here, there could be any number of persons.
On a flat disk moving upwards, you will experience the same sensation no matter where the wheel stands on the disk surface. You will feel more than 1g of weight when rising up and exactly 1g at the topmost point. Then you start free falling on the downward spin, feeling lighter, maybe weightless, depending on the spining velocity. At the lowest point you experience normal weight at 1g again and so forth.
On a globe this is different. If the Ferris wheel stands on the equator and is aligned with the globe's rotation, you are accelerated a little faster on the upward motion. If the wheel is aligned perpendicular to the globe's rotation the acceleration forces are similar to those on an upward moving disk (except there are small forces pressing you towards the side). On either pole those additional "catapulting" forces would not be experienced.