It's been a while since I thought about QFT, but the following thing was puzzling me. I've often read that theories with a beta function that is asymptotically free at lowest order will likely suffer non-perturbative effects at low energies.
For example, Srednicki's text (page 434) notes:
[T]he gauge coupling in quantum chromodynamics gets weaker at high energies, and stronger at low energies. This has dramatic physical consequences. Perturbation theory cannot serve as a reliable guide to the low-energy physics. And indeed, in nature we do not see isolated quarks or gluons. (Quarks, in particular, have fractional electric charges and would be easy to discover.) The appropriate conclusion is that color is confined: all finite-energy states are invariant under a global $SU(3)$ transformation. This has not yet been rigorously proven, but it is the only hypothesis that is consistent with all of the available theoretical and experimental information.
However, the beta function for QCD depends on the number of fermions $n_F$ like $-(C_1 - C_2 n_F) \alpha^2$ at lowest order. From that same page, it looks like for $17$ or more fermion species (quark flavors), the beta function's leading coefficient is positive and hence the beta function is not asymptotically free at lowest order.
This motivates my question: For $17$ or more fermion species, is the corresponding theory no longer confined?
