The CNO cycle is a catalytic fusion reaction that produces energy in stars larger than the sun. It converts four protons into a helium-4 nucleus using a cycle of carbon, nitrogen, and oxygen isotopes as catalysts and releases $26.7$ MeV of energy mostly in the form of gamma rays.
Could one make this cycle work in the laboratory by bombarding a cold, high-density target made of these isotopes with protons accelerated in a particle accelerator?
If a carbon nucleus has a radius of about $2.7\times10^{-15}$ m, then one would require protons to be accelerated to about $3.2$ MeV in order to overcome the Coulomb repulsion. I guess this can easily be achieved. If the energy of the gamma rays were captured, perhaps one could produce fusion energy by this method?