In quantum field theory, a subtraction scheme is a way of splitting a Lagrangian $\mathcal{L}$ into a finite piece and a counterterm piece, $$\mathcal{L} = \mathcal{L}_f + \mathcal{L}_{ct}.$$ For example, in the on-shell scheme, $\mathcal{L}_f$ is set so its terms have the same coefficients as the corresponding terms in the 1PI effective action, evaluated at the pole masses, the real physical masses of the particles. By contrast, in the $\overline{\mathrm{MS}}$ scheme the counterterms are instead defined so that they have a simple canonical form.
As a result, the parameters in $\mathcal{L}_f$ depend upon the DR mass scale $\mu$. The coupling $g(\mu)$ has a nice physical interpretation: it is an estimate of the true interaction strength for a process at energy scale $\mu$ (see here). Quantitatively, if the 1PI effective action contains $$S^{\text{eff}} \supset f(q) \bar{\psi} \tilde{A}(q)\psi$$ then we have $g(\mu) \approx f(\mu)$.
However, I've never seen a physical interpretation of the $\overline{\mathrm{MS}}$ mass $m^2(\mu)$. It is not equal to the physical mass of the particle, i.e. the pole mass, as this quantity does not depend on $\mu$. In the case of the top quark, it is significantly different.
Does the $\overline{\mathrm{MS}}$ mass have a physical meaning? Can I conclude anything from the knowledge that it is, say, bigger than the pole mass? In general, what do renormalized masses mean?