While this question is probably more at home on EE.SE, the implications can be quite profound when troubleshooting automotive problems.
If I want to test for continuity on a 12 V circuit with next to no load, can I safely do so with the multimeter set to resistance mode?
An example use case would be when testing for fuel injector signal:
if resistance mode behaves more like current mode (negligible resistance), in the absence of the injector a live circuit can generate excessively high current that could burn the ECU.
if resistance mode behaves like voltage mode (very high resistance), there should be no problems with using it for this particular application.