The overvoltage protection circuit subject is complex and there simply isn't a one size fits all remedy. Things to consider are: where will the circuit be located in relation to the service entrance, are you attempting to protect for short and/or long duration surges, and what type of surge are you planning on protecting against? From my research, the best attempt at a one size fits all overvoltage protection scheme would include line conditioning filtering (inductors/capacitors), (MOV) Metal Oxide Varistors with integral thermal disconnect fuses and Silicon Avalanche Suppressor Diodes. I would talk to the engineers at Littlefuse for advice. They have a large library of downloadable PDF's pertaining to Overvoltage Suppression.