If you're using 16.04, the best way to create a bootable USB stick is to use dd.
sudo dd if=path_to_ISO_file of=/dev/sdx bs=4M && sudo sync
Warnings
sdx represents the device letter for the USB stick. It can be sda, sdb, sdc etc, so make sure you type the correct letter over there otherwise you may delete the contents of another drive irreversibly.
Make sure there are no spaces in the path_to_iso_file.
The best way to find the appropriate key to invoke the DIOS boot menu, is to consult your motherboard manual, since every M/B uses a different one. If you can't find it, you have to change the device boot order in the BIOS settings so that it boots from USB first.