William Howe may refer to:
- William Howe, 5th Viscount Howe (1729–1814), British general during American Revolutionary War
 - William Howe (architect) (1803–1852), patented Howe truss for covered bridges
 - William Howe (mayor) (1864–1952), newspaperman in Victoria, Australia
 - William B. W. Howe (1824–1894), Bishop of South Carolina
 - William Dean Howe (1916–1982), Canadian Member of Parliament
 - William F. Howe (lawyer) (1828–1902), American trial lawyer, founded Howe and Hummel
 - William F. Howe (general) (1888–1952), American stockbroker and military leader during World Wars
 - William Henry Howe (1846–1929), American painter
 - William T. Howe (1835–1918), farmer and political figure in New Brunswick, Canada
 - William Wirt Howe (1833–1909), Justice of the Louisiana Supreme Court
 - Bill Howe (1922–2007), baseball player at Yale University
 - W. B. W. Howe Jr., (1851-1912), architect, son of the bishop
 
See also
- Will D. Howe (1873–1946), American educator, editor, and writer
 
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