Wickliffe may refer to:
People
- Charles A. Wickliffe (1788—1869), a U.S. Representative from Kentucky
 - Dean Wickliffe, a New Zealander convicted of murder
 - John Wickliffe or John Wycliffe (c. 1320–1384), English philosopher, theologian, preacher, translator, reformer and teacher
 - Letty M. Wickliffe (1902-2001), African-American educator
 - Robert C. Wickliffe, (1819—1895), Lieutenant Governor and Governor of Louisiana
 - Robert Charles Wickliffe, (1874–1912, grandson of Charles A. Wickliffe and cousin of John Crepps Wickliffe Beckham), a U.S. Representative from Louisiana
 
Places
- in Australia
 
- in the United States
 
See also
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