Wateree may refer to:
- Wateree people, a Native American tribe in the interior of the present-day Carolinas, USA
 - Wateree River, a tributary of the Santee River in central South Carolina in the United States
 - Wateree, South Carolina, a community in the United States
 - Lake Wateree, a reservoir in Kershaw, Fairfield, and Lancaster counties, South Carolina
 - USS Wateree, one of three ships that carried the name Wateree
 
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