Vasco may refer to:
People
Given name
Middle Ages
- Vasco da Gama (c. 1460s–1524), Portuguese explorer
 - Vasco Núñez de Balboa (1475-1519), Spanish conquistador
 - Vasco Fernandes Coutinho, captain of Espírito Santo (1490–1561), Portuguese nobleman and first donatary of the Captaincy of Espírito Santo
 - Vasco Fernandes (artist) (1475–1540), Portuguese painter
 - Vasco de Quiroga (1470/78–1565), Spanish bishop and judge, first bishop of Michoacán, Mexico
 - Vasco Martins de Sousa (1320s–1387), Lord of Mortágua and Chancellor mor under King Peter I of Portugal
 
Modern world
- Vasco Cordeiro (born 1973), Portuguese politician
 - Vasco da Gama Fernandes (1908–1991), Portuguese politician, Chairman of the Portuguese Parliament
 - Vasco Fernandes (footballer) (born 1986), Portuguese footballer
 - Vasco Gonçalves, Portuguese army officer and Prime Minister of Portugal from 1974 to 1975
 - Vasco Lopes (born 1999), Portuguese footballer
 - Vasco Oliveira (footballer, born 1922), Portuguese deceased footballer
 - Vasco Oliveira (footballer, born 2000), Portuguese footballer
 - Vasco Joaquim Rocha Vieira, last Portuguese governor (1991–1999) of Macau
 - Vasco Rossi (born 1952), Italian singer-songwriter
 - Vasco Santana (1898–1958), Portuguese actor
 - Vasco Sousa (footballer) (born 2003), Portuguese footballer
 
Surname
- André Vasco (born 1984), Brazilian actor and television presenter
 - Giambattista Vasco (1733–1796), Italian economist and abbot
 - María Vasco (born 1975), Spanish race walker
 - Maurizio Vasco (born 1955), American television presenter
 
Nickname or stage name
- Vassil Evtimov (born 1977), French-Bulgarian former professional basketball player and head coach nicknamed "Vasco"
 - Bill Stax, South Korean rapper Shin Dong-yeol (born 1980), former stage name Vasco
 
Sports clubs
- CR Vasco da Gama, Rio de Janeiro, Brazil, a sports club also known simply as Vasco
 - Vasco Esporte Clube, Sergipe, Brazil, a football club
 - Vasco SC, Goa, India, a sports club
 
Other uses
- Basque language, called vasco in Spanish
 - Vasco da Gama, Goa, a city in India, often called simply Vasco
 - Vasco Road, California, United States
 - Vasco (album), a two-part EP by Ricardo Villalobos
 - Jane Vasco, the lead character in the Painkiller Jane TV series
 - × Vascostylis or Vasco, an orchid genus
 - Vasco Data Security International, a corporate security firm now known as OneSpan
 - Vietnam Air Services Company, a regional airline in southern Vietnam, a subsidiary of Vietnam Airlines
 
See also
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