Twopence or tuppence may refer to:
- Two pence (or pennies) in British coinage, or the specific coins:
 - Tuppence (detective), a recurring character in the works of Agatha Christie
 - Tuppence Middleton, an English actress
 - 'Tuppence' Moran, a nickname for Desmond Moran, member of the Moran family of Melbourne-based criminals
 - My two penn'orth, an idiomatic expression
 
See also
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