Thomas Pope (1507–1559) was founder of Trinity College, Oxford.
Thomas Pope may also refer to:
- Thomas Pope (actor) (died 1603), comedian and acrobat
 - Thomas Pope, 2nd Earl of Downe (1622–1660), English Royalist
 - Thomas Pope (Canadian politician) (1825–1863), mayor of Quebec City
 - Thomas A. Pope (1894–1989), American Medal of Honor recipient
 - Tom Pope (born 1985), English football player
 - Thomas Pope (MP for Gloucester) (died 1400), English politician
 - Tommy Pope (born 1979), American stand-up comedian, writer, and actor
 - Tommy Pope (politician) (born 1962), American politician in South Carolina
 
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