St. Isidore or Saint-Isidore may refer to:
People
- Isidore of Chios (d. 251), martyr from Roman Egypt
 - Isidore of Scété (died c. 390), Egyptian priest and desert ascetic
 - Isidore of Pelusium (d. c. 450), monk from Roman Egypt
 - Isidore of Seville (c. 560–636), scholar and Archbishop of Seville, Spain
 - Isidore the Laborer (c. 1070–1130), peasant and patron saint of Madrid, Spain
 
Places
Canada
Elsewhere
- St. Isidore Island, Antarctica
 - St Isidore's, Queensland, Australia, a homestead
 - St. Isidore Cathedral, Holguín, Cuba
 - Saint Isidore Cemetery, Madrid, Spain
 
See also
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