A sica is an Illyrian, Thracian, Dacian, and Roman sword or dagger.
Sica may also refer to:
- Mario Sica (born 1936), Italian diplomat
 - Jessica Jung (nicknamed "Sica") (born 1989), Korean American singer
 - Sica Ho (born 2000), Hong Kong singer
 
SICA may refer to:
- Central American Integration System (Spanish: Sistema de la Integración Centroamericana)
 - Solomon Islands Christian Association
 - South Inter-Conference Association
 - South Indian Cultural Association, Hyderabad
 - South Indian Cultural Association, Indore
 - Subud International Cultural Association
 
See also
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