Second degree may refer to:
- A postgraduate degree or a professional degree in postgraduate education
 - Second-degree burn
 - Second-degree polynomial, in mathematics
 - Second-degree murder, actual definition varies from country to country
 - The second degree in Freemasonry
 
See also
- First degree (disambiguation)
 - Third degree (disambiguation)
 - Minute and second of arc, a second of arc being 1/3600 of a degree
 
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