Samuel Lee may refer to:
- Samuel Lee (English minister) (1625–1691), English Puritan
 - Samuel Lee (linguist) (1783–1852), English Orientalist and linguist
 - Samuel Lee (judge) (1756–1805), businessman, judge and politician in New Brunswick
 - Samuel Lee (American minister) (1803–1881), American minister, author, and legislator
 - Samuel Phillips Lee (1812–1897), Civil War rear admiral
 - Samuel Jones Lee (1844–1895), politician and lawyer from South Carolina
 - Samuel Tak Lee (born 1939), Hong Kong property billionaire
 - Sammy Lee (diver) (Samuel Lee, 1920–2016), American diver and physician
 
See also
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