Saint Constantine may refer to:
- Constantine I (c. 272 – 337), Roman Emperor and a convert to Christianity
 - Constantine of Dumnonia (6th century), King of Cornwall
 - Constantine of Strathclyde (6th century), probably fictitious King of Strathclyde
 - Constantine (British saint), various figures of this name
 - Constantine the Jew (fl. c.850–886), Byzantine monk
 - Constantine XI, last Byzantine emperor, unofficial Catholic Saint
 - St Cyril, born Constantine, Christian theologian from Thessalonica and Christian missionary among the Slavs with his brother Methodius
 
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