Rome–Constantinople schism may refer to:
- Rome–Constantinople schism of 484, also known in Western sources as the Acacian Schism
 - Rome–Constantinople schism of 863, also known in Western sources as the Photian Schism
 - Rome–Constantinople schism of 1054, also known as the Great East-West Schism
 
See also
- Moscow–Constantinople schism (disambiguation)
 - Orthodox schism (disambiguation)
 - Schism (disambiguation)
 
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