Mocambo may refer to:

• Mocambo (settlement), a type of village-sized community composed mainly of runaway slaves in colonial Brazil
• Mocambo (nightclub), a nightclub in West Hollywood, California, United States
• Mocambo (restaurant), a restaurant in Kolkata, West Bengal, India
• El Mocambo, a live music and entertainment venue in Toronto, Ontario, Canada
• Theobroma bicolor, commonly known as the mocambo tree, a Central and South American species which produces edible fruit and is related to the better-known Theobroma cacao (cocoa tree)