Manche is a French department in Lower Normandy.
Manche or La Manche may also refer to:
- English Channel (French: la Manche)
 - Daniel Manche (born 1993), American child actor
 - French frigate Manche (1806)
 - La Manche, Newfoundland and Labrador, a former community in Canada
 - La Manche Provincial Park, in Newfoundland and Labrador, Canada
 - Manche Ch'ol, a former Maya people
 - Manche Sanchez, a character on the television series Prison Break
 - Neck (music), part of musical instruments, particularly used in French music
 
See also
- La Mancha, a region of Spain
 
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