Makhanya is a surname. Notable people with the surname include:
- Joseph Makhanya (born 1981), South African footballer
 - Leonard Makhanya (born 1964), Swazi boxer
 - Mapaseka Makhanya (born 1985), South African middle and long-distance runner
 - Mondli Makhanya, South African journalist
 - Sibonelo Makhanya (born 1996), South African cricketer
 
See also
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