John Tyler (1790–1862) was the president of the United States from 1841 to 1845.
John Tyler may also refer to:
- John Tyler Sr. (1747–1813), father of President Tyler and Governor of Virginia
 - John Tyler Jr. (1819-1896), son of President Tyler and his first wife, Letitia Christian Tyler
 - John Alexander Tyler (1848–1883), second son of President Tyler and his second wife, Julia Gardiner Tyler
 - John Tyler (bishop) (1640–1724), Bishop of Llandaff
 - John Poyntz Tyler (1862–1931), Episcopal bishop, nephew of President Tyler
 - John Tyler (doctor) (1764-1841), ophthalmologist
 
See also
- John Tyler High School
 - John Tyler Community College, renamed Brightpoint Community College in 2021
 - Johnny Tyler (1918–1961), American singer
 - Johnnie Tyler (1906–1972), American baseball player
 - Tyler Prize for Environmental Achievement, established by John and Alice Tyler in 1973
 
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