ICER may refer to:
- ICER (file format), a wavelet-based image compression file format used by the NASA Mars Rovers
 - Icer, a character in the Masters of the Universe franchise
 - Institute for Clinical and Economic Review, a Boston-based nonprofit organization seeking to improve healthcare
 - Incremental cost-effectiveness ratio
 - International Computing Education Research, an annual research workshop sponsored by SIGCSE
 
See also
- Icer Air, stylized as ICER AIR, an urban big-air ski and snowboard event held in San Francisco from 2005 through 2008
 
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