Helmholtz most commonly refers to Hermann von Helmholtz (1821-1894), German physician and physicist.
Helmholtz or Helmholz may also refer to:
- Places named after the German physicist:
 - Helmholtz Association of German Research Centres
 - A. Carl Helmholz (1915-2003), an American nuclear physicist
 - Anna von Helmholtz (1834–1899), German salonnière, writer and translator
 - Lindsay Helmholz (1909-1993), an American chemist
 - Helmholtz Watson, a character in Aldous Huxley's Brave New World
 - Helmholtz equation, the eigenvalue problem for the Laplacian operator
 
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