GU, Gu, or gu may refer to:
Arts and entertainment
Music
- Gu (instrument), Chinese drums
- Bangu (drum) (Chinese: 板鼓; pinyin: bǎngǔ) or Gu (Chinese: 鼓; pinyin: gǔ), a Chinese "flowerpot" drum
 
 - Global Underground, an electronic dance music compilation series
 
Other media
- GU Comics, an online comic
 - .hack//G.U., a video game series
 - Godzilla: Unleashed, a video game
 
Universities
- Gandhara University, Peshawar, Khyber Pakhtunkhwa, Pakistan
 - Gannon University, Erie, Pennsylvania, United States
 - Gauhati University, Guwahati, Assam, India
 - Gemeente Universiteit, or Universiteit van Amsterdam, Amsterdam, Netherlands
 - Georgetown University, Washington D.C., United States
 - Ghazi University, Dera Ghazi Khan, Punjab, Pakistan
 - GIFT University, Gujranwala, Punjab, Pakistan
 - Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan
 - Gonzaga University, Spokane, Washington, United States
 - University of Gothenburg, Gothenburg, Sweden (Swedish: Göteborgs universitet)
 - Grantham University, Kansas City, Missouri, United States
 - Griffith University, several campuses in Brisbane and the Gold Coast area, Australia
 - Guangxi University, Nanning, Guangxi, China
 - Guangzhou University, Guangzhou, Guangdong, China
 - University Of Guilan, Guilan, Rasht, Iran
 - Guizhou University, Guiyang, Guizhou, China
 - Gujrat University, Gujrat, Punjab, Pakistan
 - Gujarat University, Ahmedabad, Gujarat, India
 
Businesses
- Gü, a company that produces a range of desserts
 - G.U., Japanese clothing brand
 - GU Energy Labs, a Berkeley, California-based company that produces sports nutrition products
 
Medicine
- Gastric ulcer, a disease of the stomach
 - Genitourinary system, the reproductive system and the urinary system considered as a whole
 
People
- Gu (surname), a surname of Chinese origin, also found in Korea
 - Gǔ (surname) 谷, meaning valley) came about when a noble family of the Zhou Dynasty was rewarded a fief in a valley area. The descendants of the family adopted the name to link their lineage to that history.
 - Gŭ (surname 古), meaning ancient) is uncommon, being the 204th most common surname in China.
 - Gū (surname) (辜) the family name Gū (meaning guilt) is very rare
 - Gǔ (surname 骨) (meaning bone) is exceedingly rare in China.
 - Gene Upshaw, an American football player
 
Places
- Green Ukraine, after the Russian Revolution of 1917, the Ukrainian Republic of the Far East
 - Gu County (Chinese: 古县), Shanxi, China
 - Gu, Iran (disambiguation) (Persian: گو), any of several places in Iran
 - Gu (administrative division) (Korean: 구), an administrative division of South Korea
 - Gu's Park, former name of Fuxing Park in Shanghai, China
 - GU postcode area, UK, covering west Surrey, north-east Hampshire, and a part of West Sussex
 - Guam (postal code GU)
 
Other uses
- Gu (god), a god in Haitian Vodou and Yoruba (Africa) mythology
 - Gu (poison) (simplified Chinese: 蛊; traditional Chinese: 蠱; pinyin: gǔ; Wade–Giles: ku), in Chinese poison sorcery
 - Gu (vessel), a Chinese wine goblet from the Shang and Zhou dynasties, also ku
 - Gujarati language (ISO 639-1 language code)
 - GU4 or GUD (𒄞), "bull" in the Sumerian language
- Gu-anna, the "Heavenly Bull", the Sumerian name for the constellation Taurus
 
 - GU, a prefix for several types of bi-pin connectors for lamp sockets
 
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