Francke is a German surname. Notable people with the surname include:
- August Hermann Francke (1663–1727), German Protestant theologian
- Arne Francke (1904–1973), Swedish horse rider
- Gloria Niemeyer Francke (1922–2008), American pharmacist and science writer
- Kuno Francke (1855–1930), educator and historian
- Malcolm Francke (born 1939), Australian cricketer
- Master Francke (c.1380–1440), German painter
- Michael Francke (1946–1989), Director of the Oregon Department of Corrections
- Paul Francke (architect) (c.1537-1615), German architect and master builder
- Paul Francke (footballer) († 1914-1918), German football player and founder member of Bayern Munich
- Paul Francke (geologist) (1897-1957), German geologist
- Paul Francke (musician) (born 1979), American musician
- Rend al-Rahim Francke (born 1949), Iraqi political activist and ambassador to the United States
- Rudolf Francke, German First World War flying ace
See also
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