Flight 243 may represent:
- Aloha Airlines Flight 243, explosive decompression on 28 April 1988
 - Windjet Flight 243, landed short of runway on 24 September 2010
 - RusAir Flight 243, crashed on 20 June 2011
 
See also
- No. 243 Squadron RAF, which may be incorrectly called a "flight" instead of a "squadron"
 
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