The First Commandment of the Ten Commandments may refer to:

• "I am the Lord thy God", under the Talmudic division of the third-century Jewish Talmud
• "Thou shalt have no other gods before me", under the Philonic division used by Hellenistic Jews and Protestants
• "Thou shalt not make unto thee any graven image", under the Augustinian division used by Roman Catholics and Lutherans

Other uses

• The First Commandment (novel), a 2007 novel by Brad Thor
• "The First Commandment" (Stargate SG-1), a television episode