Farfán is a Spanish surname. Notable people with the surname include:
- Alirio Farfán, Colombian cinematographer
 - Aura Elena Farfán, Guatemalan human rights activist
 - Cristina Farfán (1846–1880), Mexican educator and writer
 - David Farfan (1936–before 2009), Trinidad and Tobago sailor
 - Gabriel Farfán (born 1988), American soccer player, twin brother of Michael
 - Jefferson Farfán (born 1984), Peruvian footballer, nephew of Rafael
 - José Martín Farfán (born 1965), Colombian cyclist
 - Juan Pablo Farfán (born 1985), Peruvian footballer
 - Marco Farfan (born 1998), American soccer player
 - Marcos Farfán de los Godos, Spanish explorer of Mexico and Arizona
 - Michael Farfan (born 1988), American soccer player, twin brother of Gabriel
 - Rafael Farfán (born 1975), Peruvian footballer, uncle of Jefferson
 - Rosa María Farfán, Mexican mathematics education researcher
 - Rubén Farfán (born 1991), Chilean footballer
 - Salvador Farfán (1932–2023), Mexican footballer
 
See also
- Farfan, a village in Iran
 
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