Edward Cross may refer to:
- Edward Cross (politician) (1798–1887), Democratic member of the United States House of Representatives from the state of Arkansas
 - Edward E. Cross (1832–1863), newspaperman and Union Army general during the American Civil War
 - Edward Cross (zoo proprietor) (1774–1854), English zoo proprietor and dealer in animals
 - Edward Cross (footballer), English footballer who played for Sheffield United
 - Edward Makin Cross (1880–1965), bishop of Spokane in the Episcopal Church
 
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