Drusilla is a given name derived from the ancient Roman cognomen Drusilla, other uses are;
- Drusilla (beetle), a genus of beetles
 - Drusilla (Buffy the Vampire Slayer), character from Buffy the Vampire Slayer
 - Drusilla (Wonder Girl), incarnation of the DC Comics character Wonder Girl
 - USS Drusilla (SP-372), a United States Navy patrol vessel in commission from 1917 to 1918
 - "Drusilla", a 1935 story by William Faulkner, later merged into The Unvanquished
 
See also
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