Derek Brown may refer to:
Sports
- Derek Brown (running back) (born 1971), American football running back for the New Orleans Saints
- Derek Brown (tight end) (born 1970), American football tight end for the New York Giants, Jacksonville Jaguars, Oakland Raiders, and Arizona Cardinals
- Derek Brown (handballer) (born 1970), American handball player
- Derek Brown (rugby union) (1932–2013), Scottish rugby union player
Others
- Derek Brown (editor) (born c. 1944), British editor of the Michelin Red Guides
- Derek Brown (mixologist) (born 1974), American writer and mixologist
- Derek Brown (musician) (born 1983), American jazz saxophonist
- Derek Brown (politician) (born 1971), American politician in Utah
See also
- Jason Derek Brown (born 1969), American fugitive and accused murderer
- Derrick Brown (disambiguation)
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