Dena is a given name derived from Dinah and may refer to:
- Dena Atlantic, American television actress
 - Dena DeRose (born 1966), American jazz pianist
 - Dena Dietrich (1928–2020), American actress
 - Dena Dubal, American neurodegenerative disease researcher
 - Dena Epstein (1916–2013), American music librarian
 - Dena Grayson (born 1971), American medical doctor
 - Dena Head (born 1970), former Women's National Basketball Association player
 - Dena G. Hernandez, neurogeneticist
 - Dena Higley (born 1958), American soap opera writer
 - Dena Kaplan (born 1989), South African-born Australian actress
 - Dena Kaye (born 1946), daughter of actor Danny Kaye
 - Dena Kennedy (fl. 21st century), New Zealand actress
 - Dena Landon (born 1978), children's fiction fantasy writer
 - Dena Schlosser (born 1969), American murderer
 - Dena Tauriello, drummer for the rock band Antigone Rising since 1998
 
See also
- Deena, another given name
 
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