DS may refer to:
- Diodorus Siculus (D.S. or DS), a first-century BCE Greek historian
 - D/s, short for dominance and submission
 - Dunajská Streda, a town in Slovakia using the car registration DS
 - Enchiridion symbolorum, definitionum et declarationum de rebus fidei et morum, book of Catholic dogma, abbreviated DS for "Denzinger-Schönmetzer"
 - DS, linguistic glossing abbreviation for "different subject" in switch-reference
 - Demon Slayer: Kimetsu no Yaiba, a popular Japanese manga series written by Koyoharu Gotōge
 
Arts and entertainment
Video games
- Nintendo DS, handheld game console
 - Deca Sports, a sports video game series
- Deca Sports, the first game of the series
 
 - Double Spoiler, a game in the Touhou Project series
 - Dark Souls, a series of action role-playing games
- Dark Souls, the first game in the series
 
 - Death Stranding, an action game
 - Don't Starve, a survival game
 
Music
- "D.S." (song), a 1995 song by Michael Jackson
 - Dal segno, a navigation marker in music notation
 - "DS 21", a 1989 song by Jane Child from Jane Child
 
Government, law, and politics
- Committee for State Security (Bulgaria), a former Bulgarian secret service
 - Democratici di Sinistra (Democrats of the Left), a former Italian political party
 - Democratic Party (Demokratska stranka), a political party in Serbia
 - Detective Sergeant, UK police rank
 - Detective Superintendent, UK and Australian police rank
 - Bureau of Diplomatic Security, in the U.S. Department of State
 
Science, technology, and mathematics
- Dwarf spiral galaxy (dS)
 - Darmstadtium, symbol Ds, a chemical element
 - Data science
 - Degree of substitution, relative density of substituent groups in a polymer
 - Dielectric spectroscopy, measuring dielectric properties of medium
 - Directional symmetry (time series)
 - Dnepropetrovsk Sputnik, a class of Soviet satellites
 
Computing and telecommunications
- DS register of X86 processor
 - Avid DS, editing and effects application
 - Delegation Signer, DNSSEC record type
 - DirectShow, Microsoft API
 - Nintendo DS
 
Mathematics
- ds (elliptic function), one of Jacobi's elliptic functions
 - dS, De Sitter space
 
Medicine
- Down syndrome, a medical condition
 - Duodenal switch, a weight-loss surgery
 
Transportation
- DS Automobiles, a French car marque
 - Citroën DS Inside (2009 car) concept car
 - Citroën DS (1955-1975) car model
 - EasyJet Switzerland (IATA code DS)
 
Weapons
See also
- All pages with titles containing DS
 - All pages with titles beginning with DS
 - D (disambiguation) for Ds the plural of "D"
 
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