DSPA is an acronym for the Dutch Society for the Protection of Animals
DSPA may also refer to:
Science
- Data Science and Predictive Analytics, a textbook authored by Ivo D. Dinov
 - DNA Specimen Provenance Assignment
 - a type of synthetic phospholipid derivative
 - Desmodus rotundus salivary plasminogen activator, basis for Desmoteplase
 
Organizations
- Pyotr Alexeyev' Resistance Movement (DSPA), a former left-wing political organization in Russia
 - Deadly Serious Party of Australia, a former political party
 - Danish School of Public Administration, a civil organization partnered with School of Senior Civil Service
 - Drone Service Providers Alliance, an organization associated with the Drone Federalism Act of 2017
 
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