DMPA can refer to:
- Depot medroxyprogesterone acetate, a birth control medication marketed under the brand name Depo-Provera
- 2,2-Dimethoxy-2-phenylacetophenone, a radical initiator
- N,N′-Dimethyl-1,3-propanediamine, a cross linking reagent
- Dimethylol propionic acid
- Des Moines Performing Arts, the organization that operates the Civic Center of Greater Des Moines
- Diploma in Medical Practisonal Aelopathy
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