Coxe is a surname, and may refer to:
- Alfred Conkling Coxe Sr., American federal judge
 - Alfred Conkling Coxe Jr., American federal judge
 - Arthur Cleveland Coxe, American bishop, son of Samuel Hanson Cox
 - Cameron Coxe, Welsh footballer
 - Daniel Coxe, English governor of West Jersey
 - Eckley Brinton Coxe, Pennsylvania Mining Company Owner, State Senator
 - Francis Coxe (fl. 1560–1575), English astrologer and quack physician
 - Henry Coxe, English scholar
 - Hopewell Coxe, American politician
 - John Coxe, adopted name of Naukane, 19th-century Hawaiian labourer
 - John Coxe (MP) (c. 1695–1783), English politician
 - Louis O. Coxe, American poet
 - Margaret Coxe, 19th century educator and writer
 - Tench Coxe, early American economist and politician
 - William Coxe (historian), English historian
 - William Coxe Jr. pioneer pomologist and a U.S. Representative from New Jersey
 
See also
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