Benignus may refer to:
- Saint Benignus of Dijon (3rd century), martyr and patron saint of Dijon, Burgundy (France)
 - Saint Benignus of Todi (d. 303), martyr at Todi, Umbria (Italy)
 - Saint Benignus of Armagh (died 467), Irish disciple of St. Patrick
 - Saint Benignus (bishop of Milan) (died 472), archbishop of Milan (Italy), 465–472
 - Saint Benignus of Malcesine, (Benigno di Malcesine) often referenced with Carus of Malcesine
 - Saint Benignus of Fontenelle (fl. 725), abbot of Fontenelle Abbey (France)
 - Benignus von Safferling (1825–1895), General of the Infantry and war minister under Otto of Bavaria
 
See also
- Benign (disambiguation)
 - Benignity, medical term
 - Benigno (disambiguation)
 - Benigni (disambiguation), surname
 
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