BTD may refer to:
- Back to December, A song by American singer-songwriter Taylor Swift from her 3rd studio album Speak Now.
- BTD (Before the Dawn)
- Bloons Tower Defense, the tower defense series by Ninja Kiwi.
- Biotinidase, the enzyme that in humans is encoded by the BTD gene.
- British trade dollar, a silver coin minted by Great Britain to facilitate trade with the Far East.
- Douglas BTD Destroyer, 1940s American torpedo/dive-bomber.
- Built to Destroy (Michael Schenker Group album), the fourth album by the Michael Schenker Group
- Built to Destroy (Incite album), the fifth album by Incite
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