Introduction
The small form factor makes the NUC too prone to overheating due dust accumulation in the CPU cooler air outlet fins
Tools
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            Start by using a Phillips head #2 screw driver to remove the lower screws on the lower case door. 
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            These screws are held in with retainers, so they won't fall out when you flip the lid. 
 
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            Lift the door, and keep an eye on the cables that connect to the NUC's motherboard. These cables are the power and data cables for the 2.5" hard drive bay. 
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            Carefully unplug the cables from the motherboard, and set the bracket aside. 
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            In the last photo, the slot for a blade SSD is marked with a red arrow. This is where you would install the blade SSD, and use a screw to hold it in place. 
 
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            Change the screw driver bit to the PH1 one. 
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            Unscrew the V-NAND SSD and carefully slide it out of its connector. 
 
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            Remove the WiFi and Bluetooth antenna cables (be extremely careful when doing this otherwise you risk to rip the base contact terminal off the PCB) 
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            Remove the stereo mic cable from the motherboard connector. 
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            Pay attetion to the WiFi cable hidden under a black piece of tape 
 
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            Use a pry tool to lift the motherboard from the casing 
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            Marked with red circles the dust signs evident on first sight 
 
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            You will need to use compressed air, a small vacuum cleaner or something similar to blast off all the stucked dust. 
 
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            This step is probably not necessary, but for the sake of completeness here it is. 
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            Remove the screws holding the CPU cooler following the numbers on them. 
 
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            Use isopropyl alcohol for this, be careful not to touch the the thermal pads on the chips around the CPU. 
 
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To reassemble your device, follow these instructions in reverse order.
30 comments
Very helpful, thank you!
Ray Wang -
Great tutorial, thanks, now my fan is very clean and quiet. Thanks for spending time to create this guide!
I did see this guide after finding out the same steps myself and having seen this guide before doing so would be very helpful.